Sepsis alert systems in EDs tied to improved outcomes, study finds

Sepsis alert systems in emergency departments were linked to improved patient outcomes, including a reduced risk of death and shorter hospital stays, according to a study published in JAMA Network Open. The systematic review and meta-analysis of 22 studies of 19,580 patients found sepsis alert systems were connected to a 19% decrease in death. The systems also were associated with improved adherence to sepsis bundle elements, particularly in reducing time to fluid administration. The authors note the potential for false alarms and call for comprehensive research to better understand the impact of sepsis alert systems, including resource overutilization and overprescribing antibiotics. An article reporting on the study also says alarm fatigue can complicate the use of sepsis alert systems.